We invented the single stranded RNA origami method (Geary, Rothemund & Andersen, Science 2014).

We developed a multi-fluorophore biosensor for easy detection in fluorescence microscopes (Selnihhin et al., ACS Nano 2018).

We designed a DNA nanovault to encapsulate and control enzymes (Grossi et al., Nature Comm. 2017).

We developed aptamer-based FRET and implemented RNA origami devices (Jepsen et al., Nature Comm. 2018).

We developed an RNA origami octahedron with 6 intrinsic siRNAs for potent knockdown (Høiberg et al., Biotechnology Journal 2018).

We visualized the molecular landscape of Streptococcus pneumoniae (Engholm et al., FEMS Microbiology Reviews 2017).

We designed DNA origami boxes with controllable lids (Andersen et al., Nature 2009).

Group picture at lab BBQ at iNANO in June 2019 (Photo by Denis Selnihhin).

Welcome to the Andersen Lab for Biomolecular Design

We design nano-scale devices using biomolecules as building blocks. Our research aims at understanding the fundamental principles of how biomolecules fold into unique and functional shapes and at using this insight to guide the design of novel nanoscale devices for both basic science and technological applications. This website provides an overview of our research group and our research and teaching activities.

Latest news

2019.09.13 | People

Cody Geary is now Assistant Professor

From the 1st of September 2019, Cody Geary has been employed as an Assistant Professor in the Andersen Lab. We look forward to continue to benefit from his vast and intuitive knowledge and understanding in RNA structures and software development.

2019.06.23 | Events

Group picture 2019

A group picture was taken at the lab BBQ by Denis Selnihhin.

2019.06.12 | People

New PostDoc: Ewan McRae

On June 7th, our new PostDoc Ewan started in our group. He previously worked in Dr. Sean McKenna's lab at the University of Manitoba, where he investigated RNA G-quadruplexes and associated helicase proteins. In our group, he will work on single-particle cryo-EM analysis of RNA-protein complexes using RNA origami scaffolds.

2019.06.04 | People

Visitor from the Turberfield Lab: Joakim Bohlin

Currently, Joakin Bohlin, a PhD student from the Turberfield lab at Oxford University is visiting our lab. Joakim is a Marie Curie Early Stage Researcher in the DNA robotics ITN. His focus is on modular assembly of DNA and RNA simulations.

2019.06.01 | Knowledge exchange

Comments for Ingeniøren

On the 1st of June, the technical news site Ingeniøren brought a news story about the achievement of producing synthetic E. coli (as described below). Ebbe Sloth Andersen was asked to comment on the findings.

More news

Upcoming events

Mon 08 Jun: 12:00-12:00 | Rome
DNA-Robotics workshop Rome
As part of the DNA Robotics PhD school Nestor will participate in the workshop in Rome.
Wed 10 Jun: 00:00-00:00 | Rome
FDN 2020
The fourth Functional DNA Nanotechnology workshop will be held in Rome from 10 to 12 of June 2020. The objective of the workshop is to share knowledge and ideas in an informal environment about functional DNA nanotechnology (nanostructures, DNA origami, etc), bioengineering, synthetic biology, DNA-based sensing, aptamers, and DNA-peptide chimera.
Mon 15 Jun: 12:00-15:08 | Aarhus
Artificial Biology Conference
ArtBio2020 aims to provide a 3-day forum for topical discussions between world-renowned scientists and researchers at different stages of their carrier. Artificial biology is an exciting, fundamental discipline that aims to mimic and/or reconstruct the structure and the function of native biomolecules and small life forms – using non-biological building blocks.